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It's produced in the body from the three amino acids cysteine, glutamic acid, and glycine and serves as the body's main detoxification compound
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While homozygous C- Glud1 −/− mice show an increase in excitatory transmission under stress-naïve conditions [14], transcriptional abnormalities implicating pyramidal neuron dysfunction in heterozygous CNS- Glud1 +/− mice are triggered by stress
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