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A study showed that clofarabine inhibited the proliferation of tumor cells by downregulating DNMT1 and inhibiting the methylation of TSG, such as PTEN, APC, and RARβ2 (Majda et al., 2010)
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Since dopamine has been associated with locomotor deficits, it can be speculated that its regulatory role on dopamine might have contributed to the improvement in locomotor activity
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