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This ion channel is thought to dial in the right amount of magnesium absorption in the intestines and may play a role in the reabsorption of magnesium in the kidneys.[ref] Magnesium, via the TRPM6 ion channel, affects blood pressure regulation in the kidneys.[ref] Variants in the TRPM6 and TRPM7 genes are associated with lower plasma magnesium levels, especially when dietary intake is borderline or insufficient
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