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Secreted from skeletal muscle, adipose tissue, liver, and other organs, exerkines act as endocrine signals linking physical activity to tissue-specific adaptations
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Indeed, supplementation with mitoCoQH2 (mitochondria-targeted analogue of CoQH2) suppresses mitochondrial lipid peroxidation and cell death after combined LDHB silencing and RSL3 treatment, consistent with the presence of LDHB in the cell fraction containing the mitochondrial inner membrane
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