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We are finalizing our policy to calculate initial payment rates for covered skin substitute products in each of the three FDA regulatory categories using the volume-weighted average ASP for skin substitute products in each group as submitted by manufacturers, when available, and the MUC when ASP is not available

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The peptide inhibits nuclear factor-κB (NF-κB) activation, a master regulator of inflammatory gene expression, while simultaneously activating peroxisome proliferator-activated receptor-γ (PPAR-γ), which promotes inflammatory resolution