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(1) Studies on the Validation of In Vivo Obesity Intervention Effects A large number of in vivo animal experiments have confirmed that it exerts significant weight‑loss and fat‑reducing effects with favorable safety profiles.In a mouse model of high‑fat diet‑induced obesity, administration of 20 mg/kg NNMTi daily for 11 days resulted in a significant reduction in body weight
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When a compound average effect is only 2 kilograms over 12 weeks, many individual participants likely saw minimal to no change, while a smaller subset may have responded more strongly, pulling the average up
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